Hypertension in women with polycystic ovary syndrome: prevalence and associated cardiovascular risk factors

Eur J Obstet Gynecol Reprod Biol. 2014 Feb:173:66-70. doi: 10.1016/j.ejogrb.2013.11.011. Epub 2013 Nov 25.

Abstract

Objective: To determine the prevalence of hypertension in women with polycystic ovary syndrome (PCOS).

Study design: Women with PCOS (n=3396) and controls (n=1891) from a Han Chinese population were analysed retrospectively in terms of ovarian appearance on ultrasound, glucose tolerance test, hormones, lipoproteins, anthropomorphic measurements and blood pressure.

Results: The prevalence of hypertension was 19.2% in the women with PCOS, which was much higher than that in the controls (11.9%). After matching for body mass index, the hypertensive PCOS group had higher glucose, insulin, homeostatic model assessment (HOMA-IR) and lipid levels than the normotensive PCOS group; these differences were significant (p<0.05).

Conclusions: Hypertensive PCOS patients had higher lipid, insulin and glucose levels than normotensive PCOS patients. It is likely that the incidence of long-term complications will be higher among the former group.

Keywords: Body mass index; Complication; Hypertension; Polycystic ovary syndrome.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Blood Glucose
  • Cardiovascular Diseases / blood
  • Cardiovascular Diseases / etiology*
  • Female
  • Humans
  • Hypertension / blood
  • Hypertension / complications
  • Hypertension / epidemiology*
  • Insulin / blood
  • Lipids / blood
  • Polycystic Ovary Syndrome / blood
  • Polycystic Ovary Syndrome / complications
  • Polycystic Ovary Syndrome / epidemiology*
  • Prevalence
  • Risk Factors

Substances

  • Blood Glucose
  • Insulin
  • Lipids