Feasibility and efficacy of a computer-based intervention aimed at preventing reading decoding deficits among children undergoing active treatment for medulloblastoma: results of a randomized trial

J Pediatr Psychol. 2014 May;39(4):450-8. doi: 10.1093/jpepsy/jst095. Epub 2013 Dec 25.

Abstract

Objective: To investigate the feasibility of a computer-based reading intervention completed by patients diagnosed with a brain tumor.

Methods: Patients were randomized to the intervention (n = 43) or standard of care group (n = 38). The intervention consisted of 30 sessions using Fast ForWord® exercises in a game-like format. Change in reading decoding scores over time since diagnosis was examined. Gender, race, parent education, parent marital status, and age at diagnosis were examined as covariates.

Results: 17 patients (39.5%) were able to complete the target goal of 30 intervention sessions. Females had significantly greater training time than males (p = .022). Age at diagnosis was associated with average training time/session for females (r = .485, p = .041). No significant differences were found in reading scores between the randomized groups.

Conclusions: The study was well accepted by families and adherence by patients undergoing radiation therapy for medulloblastoma was moderate. Suggestions for improved methodology are discussed.

Keywords: academic functioning; cancer and oncology; children; cognitive assessment; intervention outcome; longitudinal research; neuropsychology.

Publication types

  • Randomized Controlled Trial
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Age Factors
  • Antineoplastic Combined Chemotherapy Protocols / adverse effects*
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Brain Neoplasms / drug therapy
  • Brain Neoplasms / psychology
  • Brain Neoplasms / radiotherapy
  • Brain Neoplasms / therapy*
  • Child
  • Child, Preschool
  • Combined Modality Therapy
  • Cranial Irradiation / adverse effects*
  • Dyslexia, Acquired / etiology
  • Dyslexia, Acquired / prevention & control*
  • Feasibility Studies
  • Female
  • Humans
  • Male
  • Medulloblastoma / drug therapy
  • Medulloblastoma / psychology
  • Medulloblastoma / radiotherapy
  • Medulloblastoma / therapy*
  • Quality of Life
  • Reading
  • Sex Factors
  • Therapy, Computer-Assisted*
  • Treatment Outcome
  • Young Adult