Geotrichum capitatum septicemia in patients with acute myeloid leukemia. Report of three cases

Fatma Saghrouni; Jihene Ben Abdeljelil; Yosra Ben Youssef; Nour Ben Abdeljelil; Soukeina Gheith; Akila Fathallah; Moncef Ben Said

doi:10.1016/j.mmcr.2012.09.003

Geotrichum capitatum septicemia in patients with acute myeloid leukemia. Report of three cases

Med Mycol Case Rep. 2012 Sep 26;1(1):88-90. doi: 10.1016/j.mmcr.2012.09.003. eCollection 2012.

Authors

Fatma Saghrouni¹, Jihene Ben Abdeljelil¹, Yosra Ben Youssef², Nour Ben Abdeljelil³, Soukeina Gheith¹, Akila Fathallah¹, Moncef Ben Said¹

Affiliations

¹ Laboratoire de parasitologie-mycologie, hôpital Farhat Hached, CHU Farhat Hached, Sousse, Tunisia.
² Service d'hématologie clinique, CHU Farhat Hached, Sousse, Tunisia.
³ Service d'hématologie clinique, Centre de greffe de moelle osseuse, Tunis, Tunisia.

Abstract

Geotrichum capitatum infection is uncommon, and has been exclusively reported in immunocompromised patients. The prognosis is poor with a mortality rate ranging from 50 to 90%. We report 3 cases of Geotrichum capitatum fungemia in neutropenic patients receiving chemotherapy for acute myeloblastic leukemia. The infection was successfully cured with voriconazole in 1 case and was fatal in the 2 remaining cases despite treatment with amphotericin B.

Keywords: Acute myeloid leukemia; Fungemia; Geotrichum capitatum; Neutropenia.