(±)-Paeoveitol, a pair of new norditerpene enantiomers from Paeonia veitchii

Org Lett. 2014 Jan 17;16(2):424-7. doi: 10.1021/ol403315d. Epub 2013 Dec 31.

Abstract

(+)-Paeoveitol and (-)-paeoveitol, a pair of new norditerpene enantiomers, were isolated from the root of Paeonia veitchii. Their structures and absolute configurations were determined on the basis of extensive analysis of 1D and 2D NMR spectra, crystal X-ray diffraction, and electronic circular dichroism (ECD). A possible biogenesis involving two molecules of paeoniflorin was postulated.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Circular Dichroism
  • Crystallography, X-Ray
  • Diterpenes / chemical synthesis
  • Diterpenes / chemistry
  • Diterpenes / isolation & purification*
  • Molecular Conformation
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Paeonia / chemistry*
  • Plant Roots / chemistry
  • Stereoisomerism

Substances

  • Diterpenes
  • paeoveitol