Imaging of non alcoholic fatty liver disease: A road less travelled

Indian J Endocrinol Metab. 2013 Nov;17(6):990-5. doi: 10.4103/2230-8210.122606.


Non alcoholic fatty liver disease (NAFLD) is a spectrum that includes simple steatosis, nonalcoholic steatohepatitis and cirrhosis. It is increasingly emerging as a cause of elevated liver enzymes, cryptogenic cirrhosis and hepatocellular carcinoma. The morbidity and mortality related to NAFLD is expected to rise with the upsurge of obesity and type 2 diabetes mellitus. The need of the hour is to devise techniques to estimate and then accurately follow-up hepatic fat content in patients with NAFLD. There are lots of imaging modalities in the radiological armamentarium, namely, ultrasonography with the extra edge of elastography, computed tomography, and magnetic resonance imaging with chemical shift imaging and spectroscopy to provide an estimation of hepatic fat content.

Keywords: Chemical shift imaging; MR spectroscopy; computed tomography; hepatic steatosis; non alcoholic fatty liver disease; sonoelastography.