[Effects of bisphenol A on the female reproductive organs and their mechanisms]

Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2013 Dec;35(6):683-8. doi: 10.3881/j.issn.1000-503X.2013.06.018.
[Article in Chinese]


Bisphenol A (BPA) is a commonly used phenolic environmental estrogen. Long-term exposure of female mammalians to BPA can lead to endocrine disorders, followed by the morphological and functional changes in ovary, uterus, vagina, and oviducts. The interactions of BPA with various target molecules or tissues will cause different effects. To further elucidate the effects of BPA on female reproductive system, we review the changes in the structure and functions of female reproduction system after BPA exposure and their possible mechanisms.

MeSH terms

  • Benzhydryl Compounds / toxicity*
  • Endocrine Disruptors / toxicity*
  • Estrogens, Non-Steroidal / toxicity
  • Female
  • Humans
  • Ovary / drug effects
  • Phenols / toxicity*
  • Uterus / drug effects
  • Vagina / drug effects


  • Benzhydryl Compounds
  • Endocrine Disruptors
  • Estrogens, Non-Steroidal
  • Phenols
  • bisphenol A