Cuff pressure of endotracheal tubes after changes in body position in critically ill patients treated with mechanical ventilation

Am J Crit Care. 2014 Jan;23(1):e1-8. doi: 10.4037/ajcc2014489.

Abstract

Background: In order to avoid microaspiration and tracheal injury, the target for endotracheal tube cuff pressure is 20 to 30 cm H2O.

Objective: To assess the effect of changes in body position on cuff pressure in adult patients.

Methods: Twelve orally intubated and sedated patients received neuromuscular blockers and were positioned in a neutral starting position (backrest, head-of-bed elevation 30º, head in neutral position) with cuff pressure at 25 cm H2O. Then, 16 changes in position were performed: anteflexion head, hyperextension head, left and right lateral flexion of head, left and right rotation of the head, semirecumbent position (head-of-bed elevation 45°), recumbent position (head-of-bed elevation 10°), horizontal backrest, Trendelenburg position (10°), and left and right lateral positioning over 30°, 45°, and 90°. Once a patient was correctly positioned, cuff pressure was recorded during an end-expiratory ventilatory hold. The pressure observed was compared with the cuff pressure at the starting position. Values outside the target range (20-30 cm H2O) were considered clinically relevant.

Results: A total of 192 measurements were performed (12 subjects × 16 positions). A significant deviation in cuff pressure occurred with all 16 changes (P < .05). No pressures were less than the lower limit (20 cm H2O). Pressures were greater than the upper limit (30 cm H2O) in 40.6% of the measurements. In each position, the upper target limit was exceeded at least once. Within-patient variability was substantial (P = .02).

Conclusion: Simple changes in patients' positioning can result in potentially harmful cuff pressures.

MeSH terms

  • Aged
  • Critical Illness / therapy*
  • Female
  • Humans
  • Intensive Care Units
  • Intubation, Intratracheal / adverse effects
  • Intubation, Intratracheal / instrumentation
  • Intubation, Intratracheal / methods*
  • Male
  • Middle Aged
  • Neuromuscular Blockade / instrumentation
  • Neuromuscular Blockade / methods
  • Patient Positioning / adverse effects
  • Patient Positioning / methods*
  • Pressure / adverse effects
  • Prospective Studies
  • Respiration, Artificial / adverse effects
  • Respiration, Artificial / instrumentation
  • Respiration, Artificial / methods*
  • Respiratory Aspiration / etiology
  • Respiratory Aspiration / prevention & control*
  • Trachea / injuries*
  • Trachea / physiopathology