The influence of β-alanine supplementation on markers of exercise-induced oxidative stress

Appl Physiol Nutr Metab. 2014 Jan;39(1):38-46. doi: 10.1139/apnm-2013-0229. Epub 2013 Jul 30.


β-Alanine (BA) has been linked with oxidative protection. This study evaluated antioxidant properties of BA. Twenty-five men consumed BA or placebo for 4 weeks, and completed a 40-min run to induce oxidative stress. Blood draws were taken to measure 8-isoprostane, total antioxidant capacity, superoxide dismutase, and glutathione. BA had no significant influence on reducing exercise-induced oxidative stress. Confidence intervals suggest a reduction in lipid peroxidation. BA supplementation may have little influence as an antioxidant.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antioxidants / pharmacology*
  • Biomarkers / blood
  • Dietary Supplements*
  • Exercise / physiology*
  • Humans
  • Male
  • Oxidative Stress / drug effects*
  • Oxidative Stress / physiology*
  • Young Adult
  • beta-Alanine / pharmacology*


  • Antioxidants
  • Biomarkers
  • beta-Alanine