Antiretroviral adherence interventions in Southern Africa: implications for using HIV treatments for prevention

Curr HIV/AIDS Rep. 2014 Mar;11(1):63-71. doi: 10.1007/s11904-013-0193-5.


There is concern that the expansion of ART (antiretroviral treatment) programmes to incorporate the use of treatment as prevention (TasP) may be associated with low levels of adherence and retention in care, resulting in the increased spread of drug-resistant HIV. We review research published over the past year that reports on interventions to improve adherence and retention in care in Southern Africa, and discuss these in terms of their potential to support the expansion of ART programmes for TasP. We found eight articles published since January 2012, seven of which were from South Africa. The papers describe innovative models for ART care and adherence support, some of which have the potential to facilitate the ongoing scale- up of treatment programmes for increased coverage and TasP. The extent to which interventions from South Africa can be effectively implemented in other, lower-resource Southern African countries is unclear.

Publication types

  • Review

MeSH terms

  • Anti-HIV Agents / administration & dosage*
  • Antiretroviral Therapy, Highly Active*
  • HIV Infections / prevention & control*
  • Humans
  • Medication Adherence*
  • South Africa


  • Anti-HIV Agents