How the motility pattern of bacteria affects their dispersal and chemotaxis

PLoS One. 2013 Dec 31;8(12):e81936. doi: 10.1371/journal.pone.0081936. eCollection 2013.

Abstract

Most bacteria at certain stages of their life cycle are able to move actively; they can swim in a liquid or crawl on various surfaces. A typical path of the moving cell often resembles the trajectory of a random walk. However, bacteria are capable of modifying their apparently random motion in response to changing environmental conditions. As a result, bacteria can migrate towards the source of nutrients or away from harmful chemicals. Surprisingly, many bacterial species that were studied have several distinct motility patterns, which can be theoretically modeled by a unifying random walk approach. We use this approach to quantify the process of cell dispersal in a homogeneous environment and show how the bacterial drift velocity towards the source of attracting chemicals is affected by the motility pattern of the bacteria. Our results open up the possibility of accessing additional information about the intrinsic response of the cells using macroscopic observations of bacteria moving in inhomogeneous environments.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacterial Physiological Phenomena*
  • Chemotaxis / physiology
  • Escherichia coli / physiology
  • Models, Biological*
  • Movement / physiology
  • Vibrio alginolyticus / physiology

Grant support

The authors acknowledge financial support by the Deutsche Forschungsgemeinschaft (DFG) through the Research Training Group GRK 1558 “Nonequilibrium Collective Dynamics in Condensed Matter and Biological Systems”. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.