[Granulosa cell tumor of the ovary: retrospective study of 17 cases]

Gynecol Obstet Fertil. 2014 May;42(5):331-3. doi: 10.1016/j.gyobfe.2013.08.010. Epub 2014 Jan 3.
[Article in French]


Granulosa cell tumors of the ovary are rare tumor of ovary, included in the sex cord-stromal tumor category, hormone secreting. Seventeen patients with adult-type granulosa cell tumor were identified between 1995 and 2012. All have received surgical treatment first at stage I. Thirty-three percent of the patients relapsed with peritoneal nodules in 68% of the cases, treated surgically and sometimes with complementary therapies, such as chemotherapy, radiotherapy, hormonal treatment. Overall survival and recurrence-free survival were 100% and 58.3%, respectively at 10 years with median time to recurrence of 6 years (4-27). These tumors have therefore a good prognosis and require long-time follow-up. Finally, the prognostic factors of recurrence identified in the literature are FIGO stage, the presence of residual tumor and tumor size.

Keywords: Facteurs pronostiques; Granulosa cell tumors; Prognostic factors; Recurrence; Récidive; Tumeur de la Granulosa.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Combined Modality Therapy
  • Female
  • Granulosa Cell Tumor / mortality
  • Granulosa Cell Tumor / pathology*
  • Granulosa Cell Tumor / therapy
  • Humans
  • Middle Aged
  • Neoplasm Recurrence, Local / epidemiology
  • Neoplasm Staging
  • Ovarian Neoplasms / mortality
  • Ovarian Neoplasms / pathology*
  • Ovarian Neoplasms / therapy
  • Prognosis
  • Retrospective Studies
  • Survival Rate

Supplementary concepts

  • Granulosa cell tumor of the ovary