Ion-driven photoluminescence modulation of quasi-two-dimensional MoS2 nanoflakes for applications in biological systems

Nano Lett. 2014 Feb 12;14(2):857-63. doi: 10.1021/nl4042356. Epub 2014 Jan 7.


Quasi-two-dimensional (quasi-2D) molybdenum disulfide (MoS2) is a photoluminescence (PL) material with unique properties. The recent demonstration of its PL, controlled by the intercalation of positive ions, can lead to many opportunities for employing this quasi-2D material in ion-related biological applications. Here, we present two representative models of biological systems that incorporate the ion-controlled PL of quasi-2D MoS2 nanoflakes. The ion exchange behaviors of these two models are investigated to reveal enzymatic activities and cell viabilities. While the ion intercalation of MoS2 in enzymatic activities is enabled via an external applied voltage, the intercalation of ions in cell viability investigations occurs in the presence of the intrinsic cell membrane potential.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adsorption
  • Biosensing Techniques / methods*
  • Disulfides / chemistry*
  • Disulfides / radiation effects
  • Glucose / analysis*
  • Glucose / chemistry
  • Glucose Oxidase / chemistry*
  • Ions
  • Luminescent Measurements / methods*
  • Molybdenum / chemistry*
  • Molybdenum / radiation effects
  • Nanoparticles / chemistry*
  • Nanoparticles / radiation effects
  • Particle Size


  • Disulfides
  • Ions
  • Molybdenum
  • Glucose Oxidase
  • Glucose
  • molybdenum disulfide