Guidance on water intake effectively improves urinary frequency in patients with nocturia

Int J Urol. 2014 Jun;21(6):595-600. doi: 10.1111/iju.12387. Epub 2014 Jan 9.


Objectives: To evaluate how guidance on water-intake impacts the degree of nocturia.

Methods: A total of 67 male patients were enrolled in the present study. Patients were asked to adjust their water and food intakes so that their 24-h urine production/bodyweight would be equal or lower than 30 mL/kg. One month after the treatment, the therapeutic gain from and adverse effects of fluid restriction were examined by comparing the pretreatment and post-treatment value of various parameters.

Results: Overall, 65 eligible patients were evaluated. In 44 patients (67%), the frequency of nocturia was improved to one or more times. The change in frequency of nocturia showed a positive correlation with the change in nocturnal urine volume. The change in nocturnal urine volume showed a positive correlation with the changes in 24-h urine production/bodyweight, 24-h drinking volume and daytime drinking volume. The changes in 24-h urine production/bodyweight and daytime drinking volume were independent factors influencing therapeutic effect. None of the participants reported any adverse event.

Conclusions: In patients with a 24-h urine production/bodyweight equal or higher than 30 mL/kg, guidance on water intake might be considered effective and safe as a lifestyle therapy. Water restriction should be carried out not only in the evening, but also during daytime.

Keywords: 24-h urine production/bodyweight; lifestyle therapy; nocturia; nocturnal polyuria; water intake guidance.

MeSH terms

  • Aged
  • Counseling
  • Drinking / physiology*
  • Humans
  • Male
  • Nocturia / drug therapy
  • Nocturia / physiopathology
  • Nocturia / therapy*
  • Water Deprivation / physiology