Parotid lymphoma: a review of clinical presentation and management

Oral Surg Oral Med Oral Pathol Oral Radiol. 2014 Jul;118(1):e1-5. doi: 10.1016/j.oooo.2013.10.013. Epub 2013 Nov 6.


Lymphoma of the parotid gland is a relatively rare occurrence among head and neck tumors. Presentation is indistinguishable from other swellings of the parotid gland; therefore, it is important to consider lymphoma in the differential diagnosis when examining parotid swellings. Parotid lymphomas are most likely to be B-cell non-Hodgkin lymphoma of 1 of 3 types, which include follicular, marginal zone, and diffuse large B cell, although other histologic patterns have been described. We present a review of 3 patients with parotid lymphoma who presented to the University of Maryland Medical Center's Department of Oral and Maxillofacial Surgery with facial swelling. Two patients were diagnosed with follicular lymphoma, whereas the third was diagnosed with marginal zone lymphoma.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Diagnosis, Differential
  • Diagnostic Imaging
  • Female
  • Humans
  • Lymphoma / diagnosis*
  • Lymphoma / pathology
  • Lymphoma / therapy
  • Male
  • Middle Aged
  • Parotid Neoplasms / diagnosis*
  • Parotid Neoplasms / pathology
  • Parotid Neoplasms / therapy
  • Radiotherapy Dosage