The range and role of palliative interventions for locally advanced breast cancer

Curr Opin Support Palliat Care. 2014 Mar;8(1):70-6. doi: 10.1097/SPC.0000000000000029.


Purpose of review: The role of palliative care interventions in patients with nonmetastatic disease is unclear. Locally advanced breast cancer (LABC) is such a diagnosis that presents a platform to examine the relationship of symptom management while patients are receiving treatment with curative intent.

Recent findings: Overwhelming physical and psychological symptoms can affect women with LABC. Fungating lesions at the time of primary presentation remain a major challenge. Treatments specifically for the treatment of fungating lesions using new dressings, topical analgesics, buccal opioids, and old techniques such as larval therapy were explored.

Summary: LABC is a complex biosocial disease that requires a collaborative interdisciplinary approach to care.

Publication types

  • Review

MeSH terms

  • Breast Neoplasms / pathology*
  • Breast Neoplasms / psychology
  • Breast Neoplasms / therapy*
  • Debridement / methods
  • Detergents / administration & dosage
  • Female
  • Hemorrhage
  • Humans
  • Infection Control / methods
  • Neoplasm Staging
  • Odorants
  • Palliative Care / methods*


  • Detergents