[Intracardiac thrombosis during celiac disease]

J Mal Vasc. 2014 May;39(3):203-6. doi: 10.1016/j.jmv.2013.12.002. Epub 2014 Jan 7.
[Article in French]

Abstract

Thrombotic events occurring in the course of celiac disease are frequently reported in the literature. The localization is often unusual, mainly affecting the hepatic veins. To our knowledge, this is the first report of intracardiac thrombosis occurring in a patient with celiac disease. A 32-year-old patient with celiac disease adhered poorly to his gluten-free diet. He suffered an ischemic stroke revealing an intracardiac thrombus, which, on radiological imaging, simulated a multiple myxoma. Histological examination of the resected tumor enabled the correct diagnosis. Biological findings revealed severe protein C and S deficiency. The patient improved with anticoagulant therapy and gluten-free diet.

Keywords: Celiac disease; Intracardiac thrombus; Maladie cœliaque; Myxoma; Myxome; Thrombophilia; Thrombophilie; Thrombus intracardiaque.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adult
  • Anticoagulants / therapeutic use
  • Celiac Disease / complications*
  • Celiac Disease / diet therapy
  • Diabetes Mellitus, Type 1 / complications
  • Diet, Gluten-Free
  • Heart Diseases / diagnosis
  • Heart Diseases / drug therapy
  • Heart Diseases / etiology*
  • Heart Neoplasms / complications*
  • Heart Neoplasms / diagnosis
  • Hemangioma, Cavernous / complications
  • Humans
  • Incidental Findings
  • Liver Neoplasms / complications
  • Magnetic Resonance Imaging, Cine
  • Male
  • Myxoma / complications*
  • Myxoma / diagnosis
  • Neoplasms, Multiple Primary / complications*
  • Neoplasms, Multiple Primary / diagnosis
  • Protein C Deficiency / complications*
  • Protein C Deficiency / diagnosis
  • Protein C Deficiency / drug therapy
  • Protein S Deficiency / complications*
  • Protein S Deficiency / diagnosis
  • Protein S Deficiency / drug therapy
  • Splenic Infarction / etiology
  • Thrombosis / diagnosis
  • Thrombosis / drug therapy
  • Thrombosis / etiology*
  • Venous Thrombosis / etiology

Substances

  • Anticoagulants