Prolonged atrial fibrillation precipitated by new-onset seizures and marijuana abuse

Pediatrics. 2014 Feb;133(2):e443-6. doi: 10.1542/peds.2013-1831. Epub 2014 Jan 13.


We report a case of prolonged atrial fibrillation (AF) precipitated by new-onset generalized tonic-clonic convulsions and marijuana abuse in a developmentally normal 18-year-old adolescent with a structurally normal heart. Our case highlights an interesting association and a unique pathophysiology between generalized tonic-clonic convulsions, marijuana abuse, and AF. We suggest that seizures and marijuana abuse should be considered in the differential diagnosis of the etiology of AF in children.

Keywords: PICU; adolescents; arrhythmia; drug abuse; seizures.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Atrial Fibrillation / etiology*
  • Epilepsy, Tonic-Clonic / complications*
  • Humans
  • Male
  • Marijuana Abuse / complications*
  • Seizures
  • Time Factors