Rebound upbeat nystagmus after lateral gaze in episodic ataxia type 2

Cerebellum. 2014 Jun;13(3):411-3. doi: 10.1007/s12311-014-0547-6.


Rebound nystagmus is a transient nystagmus that occurs on resuming the straight-ahead position after prolonged eccentric gaze. Even though rebound nystagmus is commonly associated with gaze-evoked nystagmus (GEN), development of rebound nystagmus in a different plane of gaze has not been described. We report a patient with episodic ataxia type 2 who showed transient upbeat nystagmus on resuming the straight-ahead position after sustained lateral gaze that had induced GEN and downbeat nystagmus. The rebound upbeat nystagmus may be ascribed to a shifting null in the vertical plane as a result of an adaptation to the downbeat nystagmus that developed during lateral gaze.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Adult
  • Ataxia / diagnosis
  • Ataxia / physiopathology
  • Child
  • Eye Movements / physiology*
  • Female
  • Fixation, Ocular / physiology*
  • Humans
  • Male
  • Mutation / genetics
  • Nystagmus, Pathologic / diagnosis
  • Nystagmus, Pathologic / genetics
  • Nystagmus, Pathologic / physiopathology*
  • Pedigree

Supplementary concepts

  • Episodic Ataxia