Erbium triflate promoted multicomponent synthesis of highly substituted imidazoles

Kandasamy Rajaguru; Rajendran Suresh; Arumugam Mariappan; Shanmugam Muthusubramanian; Nattamai Bhuvanesh

doi:10.1021/ol403456b

Erbium triflate promoted multicomponent synthesis of highly substituted imidazoles

Org Lett. 2014 Feb 7;16(3):744-7. doi: 10.1021/ol403456b. Epub 2014 Jan 15.

Authors

Kandasamy Rajaguru¹, Rajendran Suresh, Arumugam Mariappan, Shanmugam Muthusubramanian, Nattamai Bhuvanesh

Affiliation

¹ Department of Organic Chemistry, School of Chemistry, Madurai Kamaraj University , Madurai 625 021, India.

PMID: 24428260
DOI: 10.1021/ol403456b

Abstract

The synthesis of highly substituted imidazole derivatives has been achieved from various α-azido chalcones, aryl aldehydes, and anilines. This multicomponent protocol employs erbium triflate as a catalyst resulting in excellent yield of the imidazoles.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Aldehydes / chemistry*
Aniline Compounds / chemistry*
Catalysis
Chalcones / chemistry*
Erbium / chemistry*
Imidazoles / chemical synthesis*
Imidazoles / chemistry
Mesylates / chemistry*
Molecular Structure

Substances

Aldehydes
Aniline Compounds
Chalcones
Imidazoles
Mesylates
Erbium