Management of gastrointestinal and liver diseases during pregnancy

Gut. 2014 Jun;63(6):1014-23. doi: 10.1136/gutjnl-2013-305418. Epub 2014 Jan 15.


In the majority of patients with chronic gastrointestinal and liver diseases, maintenance therapy is required during pregnancy to control the disease, and disease follow-up or disease control might necessitate endoscopy. Evidence on the safety of drugs and imaging techniques during pregnancy is scarce and sometimes difficult to interpret. In this review we summarise existing literature with the aim of optimising counselling of patients with common chronic gastrointestinal and liver diseases who want to conceive.

Keywords: Diagnostic and Therapeutic Endoscopy; Functional Bowel Disorder; Gastroesophageal Reflux Disease; IBD; Liver.

Publication types

  • Review

MeSH terms

  • Female
  • Gallstones / diagnostic imaging
  • Gallstones / therapy
  • Gastrointestinal Diseases / diagnostic imaging
  • Gastrointestinal Diseases / drug therapy*
  • Gastrointestinal Diseases / surgery
  • Humans
  • Liver Diseases / diagnostic imaging
  • Liver Diseases / drug therapy*
  • Liver Diseases / surgery
  • Magnetic Resonance Imaging
  • Pancreatitis / diagnostic imaging
  • Pancreatitis / therapy
  • Pregnancy
  • Pregnancy Complications / diagnostic imaging
  • Pregnancy Complications / drug therapy*
  • Pregnancy Complications / surgery
  • Tomography, X-Ray Computed
  • Ultrasonography