Effect of caffeine ingestion on torque and muscle activity during resistance exercise in men

Muscle Nerve. 2014 Oct;50(4):523-7. doi: 10.1002/mus.24179. Epub 2014 Jul 14.


Introduction: We examined the effect of caffeine ingestion on muscle torque production and muscle activity at different contraction speeds in trained men.

Methods: 10 men (mean age ± SD=22 ± 1.1 years) volunteered to participate. A double-blind, randomized cross-over design was used. Sixty minutes postingestion of caffeine (6 mg kg(-1) ) or placebo, participants completed 6 repetitions of isokientic knee extension at 3 angular velocities (30°s(-1) , 150°s(-1) , 300°s(-1) ) from which peak torque was determined. Electromyographic activity of the vastus medialis was also collected.

Results: Repeated measures analysis of variance indicated that muscle torque production was significantly higher (P=0.02) with caffeine compared with placebo. A significant (P=0.02) substance by velocity interaction for muscle activity indicated significantly higher vastus medialis muscle activity in the presence of caffeine versus placebo, and this difference was amplified as angular velocity increased.

Conclusions: Acute caffeine ingestion improves muscle performance and increases muscle activity during short-duration maximal dynamic contractions.

Keywords: dynamic contractions; electromyography; ergogenic; isokinetics; muscle; nutrition.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Analysis of Variance
  • Caffeine / pharmacology*
  • Central Nervous System Stimulants / pharmacology*
  • Cross-Over Studies
  • Double-Blind Method
  • Electromyography
  • Humans
  • Male
  • Muscle Contraction / drug effects
  • Muscle, Skeletal / drug effects*
  • Physical Endurance / drug effects*
  • Quadriceps Muscle / innervation
  • Resistance Training*
  • Torque*
  • Young Adult


  • Central Nervous System Stimulants
  • Caffeine