Adoptive immunotherapy-in particular, T-cell therapy-has recently emerged as a useful strategy with the potential to overcome many of the limitations of antiviral drugs for the treatment of viral complications after hematopietic stem cell transplantation. In this review, we briefly summarize the current methods for virus-specific T-cell isolation or selection and we report results from clinical trials that have used these techniques, focusing specifically on the strategies aimed to broaden the application of this technology.
Keywords: T cell; immunotherapy; stem cell transplantation; virus.
Copyright © 2014 International Society for Cellular Therapy. Published by Elsevier Inc. All rights reserved.