Extrinsic pulmonary stenosis in primary mediastinal B-cellular lymphoma

J Clin Ultrasound. 2015 Jan;43(1):68-70. doi: 10.1002/jcu.22133. Epub 2014 Jan 22.

Abstract

We describe the case of a 34-year-old man with a history of asthenia and excessive fatigability. Transthoracic echocardiography showed a mass in the right ventricular outflow tract with a peak systolic gradient of 52 mmHg. Contrast-enhanced CT confirmed the presence of a lobulated mass, which extensively filled the anterior mediastinum, infiltrating the pulmonary artery trunk up to occupying the right ventricular outflow tract. CT-guided biopsy revealed primary mediastinal B-cellular lymphoma. The patient underwent chemotherapy, achieving complete remission of the disease at the 12-month follow-up, while the gradient across the pulmonary artery dropped from 52 mmHg to 14 mmHg.

Keywords: computer tomography; echocardiography; right-ventricular outflow-tract obstruction.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Biopsy
  • Contrast Media
  • Diagnosis, Differential
  • Follow-Up Studies
  • Humans
  • Lymphoma / diagnosis*
  • Lymphoma / drug therapy
  • Male
  • Mediastinal Neoplasms / diagnosis*
  • Mediastinal Neoplasms / drug therapy
  • Pulmonary Artery / diagnostic imaging*
  • Pulmonary Artery / pathology
  • Pulmonary Valve Stenosis / etiology*
  • Radiographic Image Enhancement
  • Tomography, X-Ray Computed
  • Ultrasonography

Substances

  • Contrast Media