A naturopathic approach to the prevention of cardiovascular disease: cost-effectiveness analysis of a pragmatic multi-worksite randomized clinical trial

J Occup Environ Med. 2014 Feb;56(2):171-6. doi: 10.1097/JOM.0000000000000066.


Objective: To determine the cost-effectiveness of a worksite-based naturopathic (individualized lifestyle counseling and nutritional medicine) approach to primary prevention of cardiovascular disease (CVD).

Methods: Economic evaluation alongside a pragmatic, multi-worksite, randomized controlled trial comparing enhanced usual care (EUC; usual care plus biometric screening) to the addition of a naturopathic approach to CVD prevention (NC+EUC).

Results: After 1 year, NC+EUC resulted in a net decrease of 3.3 (confidence interval: 1.7 to 4.8) percentage points in 10-year CVD event risk (number needed to treat = 30). These risk reductions came with average net study-year savings of $1138 in societal costs and $1187 in employer costs. There was no change in quality-adjusted life years across the study year.

Conclusions: A naturopathic approach to CVD primary prevention significantly reduced CVD risk over usual care plus biometric screening and reduced costs to society and employers in this multi-worksite-based study. Trial Registration clinicaltrials.gov Identifier: NCT00718796.

Publication types

  • Pragmatic Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Canada
  • Cardiovascular Diseases / economics
  • Cardiovascular Diseases / prevention & control*
  • Cost-Benefit Analysis
  • Diet Therapy / economics
  • Directive Counseling / economics
  • Female
  • Health Care Costs / statistics & numerical data
  • Health Promotion / economics
  • Humans
  • Male
  • Middle Aged
  • Naturopathy / economics*
  • Naturopathy / methods
  • Occupational Health Services / economics*
  • Occupational Health Services / methods
  • Primary Prevention / economics*
  • Primary Prevention / methods
  • Quality-Adjusted Life Years
  • Risk Reduction Behavior

Associated data

  • ClinicalTrials.gov/NCT00718796