Improvement in erectile function following weight loss in obese men: the SHED-IT randomized controlled trial

Obes Res Clin Pract. 2013 Dec;7(6):e450-4. doi: 10.1016/j.orcp.2013.07.004.


In a randomized controlled trial 145 sexually active overweight/obese men received either a male only SHED-IT (Self Help Exercise and Diet Using IT) weight loss program or a wait-list control. Erectile function (IIEF-5) was compared between men in the active intervention versus controls. IIEF-5 was assessed at baseline, 3 months (post-intervention) and 6 months (3-month follow-up). Intention-to-treat analysis revealed a significant intervention effect for erectile function (p = 0.018) at 6 months (+1.4; 95% CI 0.3,2.4; d = 0.32). A minimal contact, gender-tailored weight loss program significantly improved men's erectile function. Further studies evaluating change in erectile function with weight loss are warranted.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Coitus
  • Diet
  • Erectile Dysfunction / etiology
  • Erectile Dysfunction / physiopathology
  • Erectile Dysfunction / therapy*
  • Exercise
  • Follow-Up Studies
  • Health Behavior
  • Humans
  • Male
  • Middle Aged
  • Obesity / complications
  • Obesity / physiopathology
  • Obesity / therapy*
  • Patient Satisfaction
  • Penile Erection*
  • Recovery of Function*
  • Surveys and Questionnaires
  • Treatment Outcome
  • Weight Loss*
  • Weight Reduction Programs*