Psychiatric Comorbidity at the Time of Diagnosis in Adults With ADHD: The CAT Study

J Atten Disord. 2016 Dec;20(12):1066-1075. doi: 10.1177/1087054713518240. Epub 2014 Jan 24.

Abstract

Objective: The CAT (Comorbilidad en Adultos con TDAH) study aimed to quantify and characterize the psychiatric comorbidity at the time of diagnosis of ADHD in adult outpatients.

Method: Cross-sectional, multicenter, observational register of adults with ADHD diagnosed for the first time.

Results: In this large sample of adult ADHD (n = 367), psychiatric comorbidities were present in 66.2% of the sample, and were more prevalent in males and in the hyperactive-impulsive and combined subtypes. The most common comorbidities were substance use disorders (39.2%), anxiety disorders (23%), and mood disorders (18.1%). In all, 88.8% patients were prescribed pharmacological treatment for ADHD (in 93.4% of cases, modified release methylphenidate capsules 50:50).

Conclusion: A high proportion of psychiatric comorbidity was observed when adult outpatients received a first-time diagnosis of ADHD. The systematic registering of patients and comorbidities in clinical practice may help to better understand and manage the prognostic determinants in adult ADHD.

Keywords: ADHD treatment; adulthood; outcome; psychiatric comorbidity; register.

Publication types

  • Multicenter Study
  • Observational Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Anxiety Disorders / epidemiology*
  • Attention Deficit Disorder with Hyperactivity / diagnosis*
  • Attention Deficit Disorder with Hyperactivity / drug therapy
  • Attention Deficit Disorder with Hyperactivity / epidemiology
  • Comorbidity
  • Cross-Sectional Studies
  • Female
  • Humans
  • Male
  • Mental Disorders / epidemiology
  • Methylphenidate / therapeutic use
  • Mood Disorders / epidemiology*
  • Outpatients
  • Prevalence
  • Sex Distribution
  • Substance-Related Disorders / diagnosis
  • Substance-Related Disorders / epidemiology*

Substances

  • Methylphenidate