Rapidly fatal "congenital lung dysplasia": a case report and review of the literature

Fetal Pediatr Pathol. 2014 Apr;33(2):109-13. doi: 10.3109/15513815.2013.878009. Epub 2014 Jan 28.


Acinar dysplasia congenital alveolar dysplasia and alveolar capillary dysplasia with misalignment of pulmonary veins belong to the diffuse developmental disorders (congenital lung dysplasia), very rare fatal disorders of infancy that occur early in lung development. A case of quickly fatal congenital lung dysplasia in a full-term infant is presented and underlines the necessity to suspect this disease in a newborn suffering from severe and refractory respiratory distress.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Fatal Outcome
  • Humans
  • Infant, Newborn
  • Lung / abnormalities*
  • Male
  • Persistent Fetal Circulation Syndrome / complications
  • Persistent Fetal Circulation Syndrome / pathology*
  • Pulmonary Alveoli / abnormalities*
  • Pulmonary Alveoli / pathology
  • Pulmonary Veins / abnormalities*
  • Respiratory Distress Syndrome, Newborn / etiology

Supplementary concepts

  • Alveolar capillary dysplasia