Validation of respiratory inductive plethysmography (LifeShirt) in obesity hypoventilation syndrome

Carly A Hollier; Alison R Harmer; Lyndal J Maxwell; Collette Menadue; Grant N Willson; Deborah A Black; Amanda J Piper

doi:10.1016/j.resp.2014.01.014

Validation of respiratory inductive plethysmography (LifeShirt) in obesity hypoventilation syndrome

Respir Physiol Neurobiol. 2014 Apr 1:194:15-22. doi: 10.1016/j.resp.2014.01.014. Epub 2014 Jan 24.

Authors

Carly A Hollier¹, Alison R Harmer², Lyndal J Maxwell³, Collette Menadue⁴, Grant N Willson⁵, Deborah A Black⁶, Amanda J Piper⁷

Affiliations

¹ Department of Respiratory and Sleep Medicine, Royal Prince Alfred Hospital, Level 11, Building 75, Missenden Road, Camperdown, NSW 2050, Australia; Clinical and Rehabilitation Sciences Research Group, Faculty of Health Sciences, The University of Sydney, Cumberland Campus C42, 75 East Street, Lidcombe, NSW 2141, Australia. Electronic address: carly.hollier@sswahs.nsw.gov.au.
² Clinical and Rehabilitation Sciences Research Group, Faculty of Health Sciences, The University of Sydney, Cumberland Campus C42, 75 East Street, Lidcombe, NSW 2141, Australia. Electronic address: alison.harmer@sydney.edu.au.
³ Faculty of Health Sciences, Australian Catholic University, Level 2, 173 Pacific Highway, North Sydney, NSW 2060, Australia. Electronic address: lyndal.maxwell@acu.edu.au.
⁴ Department of Respiratory and Sleep Medicine, Royal Prince Alfred Hospital, Level 11, Building 75, Missenden Road, Camperdown, NSW 2050, Australia. Electronic address: collette.menadue@sswahs.nsw.gov.au.
⁵ Faculty of Health, University of Canberra, Building 12, Level D, ACT 2601, Australia. Electronic address: grant.willson@canberra.edu.au.
⁶ Ageing, Work and Health Research Group, Faculty of Health Sciences, The University of Sydney, Cumberland Campus C42, 75 East Street, Lidcombe, NSW 2141, Australia. Electronic address: deborah.black@sydney.edu.au.
⁷ Department of Respiratory and Sleep Medicine, Royal Prince Alfred Hospital, Level 11, Building 75, Missenden Road, Camperdown, NSW 2050, Australia. Electronic address: amanda.piper@sswahs.nsw.gov.au.

PMID: 24468468
DOI: 10.1016/j.resp.2014.01.014

Abstract

Validation of respiratory inductive plethysmography (LifeShirt system) (RIPLS) for tidal volume (VT), minute ventilation (V˙E), and respiratory frequency (fB) was performed among people with untreated obesity hypoventilation syndrome (OHS) and controls. Measures were obtained simultaneously from RIPLS and a spirometer during two tests, and compared using Bland Altman analysis. Among 13 OHS participants (162 paired measures), RIPLS-spirometer agreement was unacceptable for VT: mean difference (MD) 3 mL (1%); limits of agreement (LOA) -216 to 220 mL (±36%); V˙E MD 0.1 L min(-1) (2%); LOA -4.1 to 4.3 L min(-1) (±36%); and fB: MD 0.2 br min(-1) (2%); LOA -4.6 to 5.0 br min(-1) (±27%). Among 13 controls (197 paired measures), RIPLS-spirometer agreement was acceptable for fB: MD -0.1 br min(-1) (-1%); LOA -1.2 to 1.1 br min(-1) (±12%), but unacceptable for VT: MD 5 mL (1%); LOA -160 to 169 mL (±20%) and V˙E: MD 0.1 L min(-1) (1%); LOA -1.4 to 1.5 L min(-1) (±20%). RIPLS produces valid measures of fB among controls but not OHS patients, and is not valid for quantifying respiratory volumes among either group.

Keywords: Hypercapnia; LifeShirt; Obesity; Obesity hypoventilation syndrome; Respiratory inductive plethysmography; Ventilation.

Publication types

Research Support, Non-U.S. Gov't
Validation Study

MeSH terms

Female
Humans
Male
Middle Aged
Obesity Hypoventilation Syndrome / diagnosis*
Obesity Hypoventilation Syndrome / physiopathology
Plethysmography / instrumentation*
Respiration
Spirometry
Tidal Volume
Waist Circumference