Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2013;13:295-320.
doi: 10.1007/978-94-007-7500-8_9.

Cobalt: Its Role in Health and Disease

Affiliations
Review

Cobalt: Its Role in Health and Disease

Kazuhiro Yamada. Met Ions Life Sci. .

Abstract

The primarily function of cobalt in humans is based on its role in cobalamin (Cbl, vitamin B12). Therefore, this chapter will focus on the physiological roles of Cbl and the importance of cobalt in human health. Cbl acts as the cofactor for two enzymes, i.e., methylmalonyl-CoA mutase and methionine synthase, in humans. Both enzymes are important for health. In addition, unlike other water-soluble vitamins, there is a unique absorption, delivery, and activation system for Cbl in mammals. Therefore, this chapter will also review the literature on the Cbl transporting system, which is crucial for Cbl function.

Similar articles

See all similar articles

Cited by 5 articles

MeSH terms

LinkOut - more resources

Feedback