X-ray phase imaging: from synchrotron to hospital

Philos Trans A Math Phys Eng Sci. 2014 Jan 27;372(2010):20130023. doi: 10.1098/rsta.2013.0023. Print 2014 Mar 6.

Abstract

With the aim of clinical applications of X-ray phase imaging based on Talbot-Lau-type grating interferometry to joint diseases and breast cancer, machines employing a conventional X-ray generator have been developed and installed in hospitals. The machine operation especially for diagnosing rheumatoid arthritis is described, which relies on the fact that cartilage in finger joints can be depicted with a dose of several milligray. The palm of a volunteer observed with 19 s exposure (total scan time: 32 s) is reported with a depicted cartilage feature in joints. This machine is now dedicated for clinical research with patients.

Keywords: X-ray; clinics; grating interferometry; phase contrast.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Hospitals*
  • Humans
  • Interferometry
  • Pilot Projects
  • Radiation Dosage
  • Radiography / instrumentation*
  • Synchrotrons*