Dengue infection in children and adolescents: clinical profile in a reference hospital in northeast Brazil

Rev Soc Bras Med Trop. Nov-Dec 2013;46(6):765-8. doi: 10.1590/0037-8682-1716-2013.


Introduction: This study aimed to describe the clinical spectrum of dengue in children and adolescents from a hyperendemic region who were admitted for hospitalization.

Methods: A retrospective study was conducted on patients diagnosed with dengue infection upon admission to a reference center in Fortaleza, Brazil.

Results: Of the 84 patients included, 42 underwent confirmatory testing. The main symptoms were fever, abdominal pain and vomiting. The median level of serum aspartate aminotransferase was 143.5±128mg/dL.

Conclusions: A peculiar clinical profile was evident among children and adolescents with dengue infection in a reference center in northeast Brazil, including gastrointestinal symptoms and liver involvement.

MeSH terms

  • Adolescent
  • Aspartate Aminotransferases / blood
  • Biomarkers / blood
  • Brazil / epidemiology
  • Child
  • Child, Preschool
  • Dengue / diagnosis
  • Dengue / enzymology
  • Dengue / epidemiology*
  • Endemic Diseases*
  • Female
  • Hospitalization
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Retrospective Studies


  • Biomarkers
  • Aspartate Aminotransferases