Turmeric: Reemerging of a Neglected Asian Traditional Remedy

J Nephropathol. 2012 Apr;1(1):17-22. doi: 10.5812/jnp.5. Epub 2012 Apr 5.

Abstract

Context: Turmeric (Curcuma longa) is a wild plant of the ginger family native to tropical South Asia.

Evidence acquisitions: Directory of Open Access Journals (DOAJ), Google Scholar, Pubmed (NLM), LISTA (EBSCO) and Web of Science have been searched.

Results: Emerging evidence indicate that turmeric/curcumin inhibits cytokines and TGF-β production. From the various factors involved in the genesis of chronic kidney disease and pathogenesis of primary and secondary glomerulonehritis, TGF-β has emerged as a key factor in the cascade of events. Leading to glomerulosclerosis, tubulointerstitial fibrosis and end-stage renal disease.

Conclusions: considering the inhibitory effect of turmeric/curcumin on cytokines and TGF-β, it seems wise to assume that supplementary turmeric/curcumin might be a candidate remedy for chronic kidney disease and possibly prevention of subsequent end stage renal disease.

Keywords: Chronic kidney disease; Curcumin; End stage renal disease; Turmeric.

Publication types

  • Review