One-step generation of knockout pigs by zygote injection of CRISPR/Cas system

Cell Res. 2014 Mar;24(3):372-5. doi: 10.1038/cr.2014.11. Epub 2014 Jan 31.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alleles
  • Animals
  • Animals, Genetically Modified
  • Base Sequence
  • Bleeding Time
  • CRISPR-Associated Proteins / metabolism*
  • Clustered Regularly Interspaced Short Palindromic Repeats / genetics*
  • Embryo Transfer
  • Factor VIII / metabolism
  • Humans
  • Mutation
  • RNA, Messenger / metabolism
  • Swine
  • Zygote / cytology
  • von Willebrand Factor / genetics
  • von Willebrand Factor / metabolism

Substances

  • CRISPR-Associated Proteins
  • RNA, Messenger
  • von Willebrand Factor
  • Factor VIII