Measurement of the time-resolved reflection matrix for enhancing light energy delivery into a scattering medium

Phys Rev Lett. 2013 Dec 13;111(24):243901. doi: 10.1103/PhysRevLett.111.243901. Epub 2013 Dec 9.


Multiple scatterings occurring in a turbid medium attenuate the intensity of propagating waves. Here, we propose a method to efficiently deliver light energy to the desired target depth in a scattering medium. We measure the time-resolved reflection matrix of a scattering medium using coherent time-gated detection. From this matrix, we derive and experimentally implement an incident wave pattern that optimizes the detected signal corresponding to a specific arrival time. This leads to enhanced light delivery at the target depth. The proposed method will lay a foundation for efficient phototherapy and deep-tissue in vivo imaging in the near future.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Electromagnetic Radiation*
  • Light*
  • Nephelometry and Turbidimetry / instrumentation
  • Nephelometry and Turbidimetry / methods*
  • Scattering, Radiation*