The acute phase response in gout

J Rheumatol. 1987 Oct;14(5):974-7.


We studied the acute phase response in gout. Oral temperature, white blood cell count and differential, platelet count, Westergren erythrocyte sedimentation rate (ESR), and serum levels of the acute phase reactants serum amyloid A protein (SAA) and C-reactive protein (CRP) were all elevated. The number of involved joints correlated with levels of ESR, SAA and CRP. CRP correlated with temperature, differential count, ESR and SAA. The acute phase response resolved rapidly with treatment.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Acute-Phase Proteins / blood*
  • Acute-Phase Reaction / blood*
  • Adult
  • Aged
  • Aged, 80 and over
  • Blood Sedimentation
  • C-Reactive Protein / metabolism
  • Gout / blood*
  • Humans
  • Inflammation / blood*
  • Leukocyte Count
  • Male
  • Middle Aged
  • Platelet Count
  • Serum Amyloid A Protein / metabolism


  • Acute-Phase Proteins
  • Serum Amyloid A Protein
  • C-Reactive Protein