Management of urinary tract infections from multidrug-resistant organisms

Infect Dis Clin North Am. 2014 Mar;28(1):49-59. doi: 10.1016/j.idc.2013.10.002. Epub 2013 Dec 8.


Antibiotic resistance worsens clinical outcomes and, in some cases, significantly impacts the clinical management of urinary tract infections in the outpatient setting. This article presents the prevalence and mechanism of relevant antimicrobial resistance patterns encountered among uropathogens, and discusses the efficacy of antibiotic regimens and novel therapies in treating commonly encountered multidrug-resistant organisms.

Keywords: Carbapenem-resistant Enterobacteriaceae; Cystitis; Extended-spectrum β-lactamases; Multidrug-resistant organisms; Vancomycin-resistant Enterococcus.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / therapeutic use*
  • Disease Management
  • Drug Resistance, Multiple, Bacterial*
  • Drug Therapy, Combination
  • Enterobacteriaceae Infections / drug therapy
  • Enterobacteriaceae Infections / microbiology
  • Escherichia coli Infections / drug therapy
  • Escherichia coli Infections / microbiology
  • Humans
  • Staphylococcal Infections / drug therapy
  • Staphylococcal Infections / microbiology
  • Urinary Tract Infections* / drug therapy
  • Urinary Tract Infections* / microbiology


  • Anti-Bacterial Agents