Multiple potassium-channel components are produced by alternative splicing at the Shaker locus in Drosophila

Nature. 1988 Jan 14;331(6152):137-42. doi: 10.1038/331137a0.

Abstract

At least four probable components of potassium channels are encoded at the Drosophila Shaker locus, by a family of alternatively spliced transcripts. Alternative splicing may provide one mechanism of generating the remarkable diversity of potassium channels.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Chromosome Mapping
  • Cloning, Molecular
  • DNA / genetics
  • DNA, Recombinant*
  • Drosophila melanogaster / genetics*
  • Ion Channels / physiology*
  • Molecular Sequence Data
  • Mutation
  • Potassium / metabolism*
  • Proteins / genetics
  • RNA Splicing
  • Transcription, Genetic

Substances

  • DNA, Recombinant
  • Ion Channels
  • Proteins
  • DNA
  • Potassium