Effects of Nε-carboxymethyl-Lysine on ERS-mediated apoptosis in diabetic atherosclerosis

Int J Cardiol. 2014 Apr 1;172(3):e478-83. doi: 10.1016/j.ijcard.2014.01.031. Epub 2014 Jan 23.

Authors

Zhongqun Wang¹, Jinchuan Yan¹, Lihua Li², Naifeng Liu³, Yi Liang¹, Wei Yuan¹, Xiaojie Chen¹

Affiliations

¹ Department of Cardiology, Affiliated Hospital of Jiangsu University, Zhenjiang 212001, China.
² Department of Pathology, Affiliated Hospital of Jiangsu University, Zhenjiang 212001, China.
³ Department and Institute of Cardiology, Zhongda Hospital, Southeast University, Nanjing 210009, China. Electronic address: liunf@seu.edu.cn.

PMID: 24491856
DOI: 10.1016/j.ijcard.2014.01.031

No abstract available

Keywords: Advanced glycation end-products; Apoptosis; Atherosclerosis; Diabetes; Endoplasmic reticulum -stress; Lipid accumulation.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Apoptosis / drug effects*
Atherosclerosis / drug therapy*
Atherosclerosis / etiology
Atherosclerosis / pathology
Blood Glucose / metabolism
Blotting, Western
Cholesterol / metabolism
Diabetes Mellitus, Experimental / complications
Diabetes Mellitus, Experimental / metabolism
Diabetes Mellitus, Experimental / pathology*
Endoplasmic Reticulum Stress*
Glycation End Products, Advanced
Immunohistochemistry
Lysine / analogs & derivatives*
Lysine / pharmacology
Male
Mice

Substances

Blood Glucose
Glycation End Products, Advanced
N(6)-carboxymethyllysine
Cholesterol
Lysine