Phytochemical and medicinal importance of Ginkgo biloba L

Nat Prod Res. 2014;28(10):746-52. doi: 10.1080/14786419.2013.879303. Epub 2014 Feb 5.


Ginkgo biloba L., also popularly known as living fossil, possesses a variety of biological and pharmacological activities. The leaf extract of G. biloba L. (EGb 761) has been used for years to treat age-related memory-deficit problems, including Alzheimer's and dementia. Experimental and clinical studies have revealed its beneficial effects on a wide range of pathological conditions including hepatoprotective, photoprotective effects, DNA repair mechanism, antioxidant and anti-inflammatory activities. Recent studies have also suggested that leaf extract of G. biloba L. may exert beneficial effects on cancer. This review focuses on recent scientific evidence of the reported medicinal effects of G. biloba L.

Keywords: Alzheimer's; EGb 761; Ginkgo biloba L; bilobalide; ginkgolide.

Publication types

  • Review

MeSH terms

  • Alzheimer Disease / drug therapy
  • Anti-Inflammatory Agents / pharmacology*
  • Anti-Inflammatory Agents / therapeutic use
  • Biological Products / pharmacology*
  • Biological Products / therapeutic use
  • Ginkgo biloba / chemistry*
  • Humans
  • Jaundice / drug therapy
  • Middle Aged
  • Molecular Structure
  • Neoplasms / drug therapy
  • Phytotherapy
  • Plant Extracts / pharmacology*
  • Plant Extracts / therapeutic use
  • Plants, Medicinal / chemistry*


  • Anti-Inflammatory Agents
  • Biological Products
  • Plant Extracts
  • Ginkgo biloba extract