Obsessive-compulsive disorder and common comorbidities

J Clin Psychiatry. 2014 Jan;75(1):e02. doi: 10.4088/JCP.13023tx1c.


Patients with obsessive-compulsive disorder (OCD) often have comorbid psychiatric disorders, such as depression, bipolar disorder, psychotic disorders, and eating disorders, which present challenges to the treating physician. Symptoms of OCD may have an earlier onset and be more severe in patients with comorbid illnesses than in those with OCD alone. Both cognitive-behavioral therapy (using exposure and response/ritual prevention) and medication may be needed to treat patients with OCD and comorbid mood, psychotic, or eating disorders.

MeSH terms

  • Age of Onset
  • Bipolar Disorder / drug therapy
  • Bipolar Disorder / epidemiology
  • Bipolar Disorder / therapy
  • Cognitive Behavioral Therapy / methods
  • Combined Modality Therapy / statistics & numerical data*
  • Comorbidity
  • Depressive Disorder / drug therapy
  • Depressive Disorder / epidemiology
  • Depressive Disorder / therapy
  • Feeding and Eating Disorders / drug therapy
  • Feeding and Eating Disorders / epidemiology
  • Feeding and Eating Disorders / therapy
  • Humans
  • Obsessive-Compulsive Disorder / drug therapy
  • Obsessive-Compulsive Disorder / epidemiology
  • Obsessive-Compulsive Disorder / therapy*
  • Psychotic Disorders / drug therapy
  • Psychotic Disorders / epidemiology
  • Psychotic Disorders / therapy
  • Severity of Illness Index