Molecular diagnostics for gonorrhoea: implications for antimicrobial resistance and the threat of untreatable gonorrhoea

PLoS Med. 2014 Feb 4;11(2):e1001598. doi: 10.1371/journal.pmed.1001598. eCollection 2014 Feb.


This Essay from Nicola Low and colleagues discusses the importance of the nucleic acid amplification tests for rapid detection of N. gonorrhoeae and its resistance determinants, as well as the importance of ensuring their rational use, as priorities for controlling both gonorrhoea and antimicrobial resistance.

Please see later in the article for the Editors' Summary

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / therapeutic use*
  • DNA, Bacterial / isolation & purification
  • Drug Resistance, Bacterial* / genetics
  • Gonorrhea / diagnosis
  • Gonorrhea / drug therapy*
  • Gonorrhea / microbiology
  • Humans
  • Microbial Sensitivity Tests
  • Molecular Diagnostic Techniques*
  • Neisseria gonorrhoeae / drug effects*
  • Neisseria gonorrhoeae / genetics
  • Neisseria gonorrhoeae / growth & development
  • Neisseria gonorrhoeae / isolation & purification
  • Nucleic Acid Amplification Techniques
  • Precision Medicine*
  • Predictive Value of Tests
  • Treatment Failure


  • Anti-Bacterial Agents
  • DNA, Bacterial