Hypothalamic tanycytes: gatekeepers to metabolic control

Cell Metab. 2014 Feb 4;19(2):173-5. doi: 10.1016/j.cmet.2014.01.008.


How circulating signals of hunger and satiety enter the brain to reach neurons that govern energy balance has long remained a matter of controversy and speculation. Balland et al. (2014) now elucidate molecular mechanisms by which a highly specialized hypothalamic glial cell regulates transport of leptin across the blood-brain barrier.

Publication types

  • Comment

MeSH terms

  • Animals
  • Brain / metabolism*
  • Ependymoglial Cells / metabolism*
  • Hypothalamus / metabolism*
  • Leptin / metabolism*
  • Male


  • Leptin