Cotton fabric finished with β-cyclodextrin: Inclusion ability toward antimicrobial agent

Carbohydr Polym. 2014 Feb 15:102:550-6. doi: 10.1016/j.carbpol.2013.11.074. Epub 2013 Dec 7.

Abstract

β-Cyclodextrin was grafted onto cotton fabric through crosslinking with butane tetracarboxylic acid in presence of sodium hypophosphite monohydrate as a catalyst. This finished cotton fabric was loaded with the antimicrobial agent octenidine dihydrochloride. β-Cyclodextrin-grafted cotton fabrics, both after loading with octenidine dihydrochloride or before loading (control) were characterized for their antimicrobial activity against two types of bacteria (Gram positive and Gram negative) and two types of fungi, using the Diffusion Disk Method. The antimicrobial cotton fabric was subjected to several washing cycles and the antimicrobial activity was measured after each washing cycle to examine the durability of this antimicrobial finishing against repeated washing. The measurements showed that the finished cotton fabrics retain reasonable deal of their antimicrobial activity, even after 20 washing cycles. This long-lasting antimicrobial activity is attributed to the hosting ability of the cavities present in cyclodextrin moieties, which host the antimicrobial agent molecules and release them gradually.

Keywords: Antimicrobial activity; Cotton fabric; Finishing; β-Cyclodextrin.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Infective Agents / chemistry*
  • Anti-Infective Agents / pharmacology
  • Cotton Fiber*
  • Gram-Negative Bacteria / drug effects
  • Gram-Positive Bacteria / drug effects
  • Microbial Sensitivity Tests
  • Temperature
  • beta-Cyclodextrins / chemistry*

Substances

  • Anti-Infective Agents
  • beta-Cyclodextrins
  • betadex