Selective deletion of Jak2 in adult mouse hematopoietic cells leads to lethal anemia and thrombocytopenia

Haematologica. 2014 Apr;99(4):e52-4. doi: 10.3324/haematol.2013.100016. Epub 2014 Feb 7.
No abstract available

Keywords: Jak2; adult hematopoiesis.

Publication types

  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anemia / genetics*
  • Anemia / mortality
  • Anemia / pathology
  • Anemia / therapy
  • Animals
  • Bone Marrow / pathology
  • Bone Marrow Transplantation
  • Crosses, Genetic
  • Gene Deletion*
  • Hematopoietic Stem Cells / metabolism*
  • Janus Kinase 2 / genetics*
  • Mice
  • Mice, Knockout
  • Mice, Transgenic
  • Thrombocytopenia / genetics*
  • Thrombocytopenia / mortality
  • Thrombocytopenia / pathology
  • Thrombocytopenia / therapy

Substances

  • Janus Kinase 2