[Primary lymphoma of the nervous system following radiculoneuritis caused by Borrelia burgdorferi: study of a case]

Schweiz Arch Neurol Psychiatr (1985). 1988;139(1):31-8.
[Article in French]


A 50-year-old man had a primary lymphoma of the central nervous system one year after a tick bite and a radiculoneuritis secondary to Borrelia burgdorferi infection. Determination of antibodies against Borrelia burgdorferi revealed increasing IgM and IgG titers, and the autopsy showed a primary B-cell immunoblastic lymphoma of the brain without evidence of extraneural lymphoproliferative disorder. Lymphoma of the brain is a rare type of central nervous system cancer, and sporadic cases appear without predisposing features such as immunosuppression or viral infection. The controversy surrounding the histogenesis of this neoplasm is reviewed: an unknown agent or a cofactor should provoke cellular proliferation and the formation of a lymphoma.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Animals
  • Bites and Stings / complications
  • Borrelia Infections / pathology*
  • Brain / pathology
  • Brain Neoplasms / pathology*
  • Humans
  • Immunoenzyme Techniques
  • Immunoglobulin M / metabolism
  • Lymphoma / pathology*
  • Male
  • Middle Aged
  • Neoplasm Recurrence, Local / pathology
  • Polyradiculoneuropathy / pathology*
  • Ticks
  • Tomography, X-Ray Computed


  • Immunoglobulin M