Chondrosarcoma of the larynx with additional malignant mesenchymal component (dedifferentiated chondrosarcoma)

Am J Surg Pathol. 1988 Apr;12(4):314-20. doi: 10.1097/00000478-198804000-00009.


Chondrosarcoma of the larynx is a rare tumor that usually is low grade both in histology and biologic aggressiveness; local ablative surgery is curative in most cases. We present a case of this tumor with additional malignant mesenchymal component, so-called dedifferentiated chondrosarcoma--an entity which, when found in other areas, has carried a much poorer prognosis.

Publication types

  • Case Reports

MeSH terms

  • Cell Differentiation
  • Chondrosarcoma / metabolism
  • Chondrosarcoma / pathology*
  • Chondrosarcoma / surgery
  • Humans
  • Immunohistochemistry
  • Laryngeal Neoplasms / metabolism
  • Laryngeal Neoplasms / pathology*
  • Laryngeal Neoplasms / surgery
  • Laryngectomy
  • Male
  • Middle Aged
  • Staining and Labeling
  • Vimentin / metabolism


  • Vimentin