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Review
, 8 (2), 287-96

Genome-wide Association Studies and the Clinic: A Focus on Breast Cancer

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Review

Genome-wide Association Studies and the Clinic: A Focus on Breast Cancer

Amélie Véron et al. Biomark Med.

Abstract

Breast cancer is the most frequently diagnosed cancer among women worldwide, and has long been considered to be a genetic disease. A wide range of genetic variants, both rare mutations and more common variants, have been shown to influence breast cancer risk. In particular, recent studies have identified a number of common genetic variants, or single nucleotide polymorphisms, that are associated with breast cancer risk. In this review, we will briefly present the genetic epidemiology of breast cancer, genome-wide association study technology and how this technology may influence breast cancer screening in the clinic.

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