Identification of artery wall stiffness: in vitro validation and in vivo results of a data assimilation procedure applied to a 3D fluid-structure interaction model

J Biomech. 2014 Mar 21;47(5):1027-34. doi: 10.1016/j.jbiomech.2013.12.029. Epub 2014 Jan 31.


We consider the problem of estimating the stiffness of an artery wall using a data assimilation method applied to a 3D fluid-structure interaction (FSI) model. Recalling previous works, we briefly present the FSI model, the data assimilation procedure and the segmentation algorithm. We present then two examples of the procedure using real data. First, we estimate the stiffness distribution of a silicon rubber tube from image data. Second, we present the estimation of aortic wall stiffness from real clinical data.

Keywords: Coarctation of the aorta; Data assimilation; Experimental validation; Fluid–structure interaction; Medical imaging; Stiffness estimation.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Validation Study

MeSH terms

  • Algorithms
  • Aorta / physiology*
  • Aortic Coarctation / physiopathology
  • Computer Simulation
  • Humans
  • Male
  • Models, Cardiovascular*
  • Vascular Stiffness*
  • Young Adult