[Critical study of current tumoral markers]

Bull Cancer. 1988;75(3):247-62.
[Article in French]

Abstract

A number of biological markers have been recently introduced in clinical use as an aid for diagnosis and monitoring of malignant tumors. Some of them are relatively tumor-specific, i.e. CA 125 for non-mucinous ovarian cancer, CA 15.3 for breast cancer, PSA for prostate cancer, CA 19.9 for colo-rectal and pancreatic cancers. The clinical usefulness, the sensitivity and specificity of these tumor markers and of a few others (CA 50, SCC and TPA) are commented in this review.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Antibodies, Monoclonal*
  • Antigens, Neoplasm / analysis*
  • Antigens, Neoplasm / immunology
  • Antigens, Tumor-Associated, Carbohydrate
  • Biomarkers, Tumor / analysis*
  • Biomarkers, Tumor / immunology
  • Chorionic Gonadotropin / analysis
  • Female
  • Humans
  • Male
  • Peptides / analysis
  • Placental Lactogen / analysis
  • Prostate-Specific Antigen
  • Tissue Polypeptide Antigen

Substances

  • Antibodies, Monoclonal
  • Antigens, Neoplasm
  • Antigens, Tumor-Associated, Carbohydrate
  • Biomarkers, Tumor
  • Chorionic Gonadotropin
  • Peptides
  • Tissue Polypeptide Antigen
  • tumor antigen TA-4, human
  • Placental Lactogen
  • Prostate-Specific Antigen