Neonatal tuberculosis and cardiac inflammatory myofibroblastic tumor

Asian Cardiovasc Thorac Ann. 2013 Apr;21(2):218-21. doi: 10.1177/0218492312451982.


A 1-month-old neonate was admitted in respiratory distress. Two-dimensional echocardiography and computed tomography scan showed a mass anterior to the left ventricle and right ventricular outflow tract. A biopsy revealed an inflammatory myofibroblastic tumor. A tuberculin test showed an 18-mm diameter induration. Three of the 6 household contacts were also positive for pulmonary tuberculosis. Antituberculosis medication was started. After 1 year, echocardiography and computed tomography scan showed complete resolution of the mass.

Keywords: Granuloma; infant; newborn; plasma cell; tuberculosis.

Publication types

  • Case Reports

MeSH terms

  • Antitubercular Agents / therapeutic use
  • Biopsy
  • Contact Tracing
  • Drug Therapy, Combination
  • Echocardiography
  • Female
  • Granuloma, Plasma Cell / diagnosis
  • Granuloma, Plasma Cell / drug therapy
  • Granuloma, Plasma Cell / microbiology*
  • Heart Diseases / diagnosis
  • Heart Diseases / drug therapy
  • Heart Diseases / microbiology*
  • Humans
  • Infant
  • Infant, Newborn
  • Time Factors
  • Tomography, X-Ray Computed
  • Treatment Outcome
  • Tuberculin Test
  • Tuberculosis, Pulmonary / complications
  • Tuberculosis, Pulmonary / diagnosis
  • Tuberculosis, Pulmonary / drug therapy
  • Tuberculosis, Pulmonary / microbiology*


  • Antitubercular Agents